I’m wondering what the difference between loratidine and fexofenadine is. They’re both the same class of drug h1 antagonist, but fexofenadine works so much better for my perennial allergies. Also why is loratidine OTC and fexofenadine isn’t since the latter has been out a lot longer?
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loratadine is a 2nd generation antihistamine, it has fewer side effects than 1st generation (i.e. diphenhydramine, fexofenadine), and greater effectiveness in a majority of patients. Granted some people will respond differently and might see better results with another agent.
The move to put it OTC is solely at the manufacturer’s discretion (at least with this class of drug). The company figured it could make more money by offering the product on the counter, where brand loyalty, as opposed to prescription co-pays, would drive sales. Notice how just recently Zyrtec went OTC at the same exact time the generic came out. It’s a common practice in the drug world. Fexofenadine, being similar to OTC antihistamines, has the potential to be offered OTC, but the manufacturer has to make that decision.
I don’t think there is a difference. When Claritin was a prescription I was on that. Then went to Zyrtec(when Claritin went otc) and now I am on Allegra( now that Zyrtec is Otc). My doctor prescribes whatever my insurance will cover.