Treximet is made by the same company that makes Imitrex. A listed contraindicated medication when taking Imitrex is naproxen, but Treximet IS a combination of naproxen and the same medication in Imitrex.
Anyone know of the new research that supports the acceptance of this?
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There is no real drug-drug interaction that occurs between Imitrex and Naproxen. Imitrex is designed to prevent vasodilation in the brain, stopping the migraine at its point of development. Most people use Naproxen to treat the pain associated with their migraine headaches, which is no problem. However, taking the two together will not allow you to tell if the Imitrex (which is quite expensive) is working properly at aborting the migraine.