can you overdose on sinemet (levodopa/carbidopa) ?

by Admin on January 14, 2010

My father takes sinemet for his parkinson’s disease. He also suffers badly from depression, especially since his wife (my mother) died. He gets loads of sinemet every week from the doctor. I’m worried about the danger of him overdosing on it. Can it kill you in overdose ?.

{ 2 comments… read them below or add one }

Straight Talker January 14, 2010 at 12:06 pm

Well yes, you can overdose, but if he is taking the recommended doseage as prescribed he should be fine.

If you are worried about a possible overdose, I would recommend getting one of those pill boxes with the days of the week on. You can fill one up for him week at a time and you can visually keep track of the pills he is taking.

I have found the below for you:

Overdosing on Sinemet CR: An Introduction
Sinemet® CR (carbidopa-levodopa CR) is a prescription drug usually used to treat Parkinson’s disease. As with any medication, it is possible to take too much Sinemet CR. The specific effects of a Sinemet CR overdose may vary, depending on a number of factors, including the dosage and whether it was taken with any other medications or substances.

Symptoms of a Sinemet CR Overdose
In cases of an overdose with levodopa (one of the components of Sinemet CR), the following symptoms were reported:

* Involuntary body movements
* Nausea and vomiting
* Rapid heart rate (tachycardia)
* Confusion or agitation
* Insomnia and restlessness
* Low blood pressure (hypotension) or high blood pressure (hypertension).

It is expected that Sinemet CR will cause similar overdose symptoms, compared to just levodopa.

Treatment for a Sinemet CR Overdose
The treatment for a Sinemet CR overdose may also vary, and there is no known antidote. If the overdose was recent, a healthcare provider may "pump the stomach" or administer certain medications to induce vomiting. Treatment may also involve supportive care, which consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options for a Sinemet CR overdose may include:

* Careful monitoring of the heart, blood pressure, and breathing
* Fluids through an intravenous line (IV)
* Other treatments based on the complications that occur.

It is important that you seek medical attention immediately if you believe that you may have overdosed on Sinemet CR.

manxbiker January 14, 2010 at 12:06 pm

if taken as prescribed by the doctor should be ok

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