Anyone took Glucophage for fertility treatment?

by Admin on September 4, 2010

The doctor prescribed Glucophage so I would ovulate and hopefully get pregnant. I’m confused as of how does it actually work and how effective is it?

I’m not diabetic, but have a very mild case of polycystic ovaries syndrome and I’m a bit overweight. The doctor said that if I lost weight and took Glucophage (500mg twice a day) I should get pregnant.

Anyone with some kind of experience with Glucophage, please share!

Thanks!

{ 4 comments… read them below or add one }

burninghalo69 September 4, 2010 at 8:46 am

I have a support group for women with PCOS and endo. We have alot of information posted on our website(including information about metformin and why it is used for PCOS) that can answer all your questions and get the support you need.
Please join us.

we are located at:

http://www.cafemom.com/group/endosupport

Hope to see you there

Here is some info about metformin for you:

Metformin is currently being used to induce ovulation in women with polycystic ovarian syndrome (PCOS). Metformin is an insulin sensitizing drug originally used in the treatment of diabetes. Metformin “reverses” insulin resistance (hyperinsulinemia) thus effectively treating many diabetics.

Up to 40- 70% of patients with PCOS have hyperinsulinemia which leads to excess androgen (male hormones) production by the ovaries and increased production of LH by the pituitary. The body tries to compensate for insulin resistance by the “over production” of insulin. Increased LH levels cause further elevations in androgens. Clinically, this results in ovulatory irregularities (or anovulation), increased body hair, numerous small ovarian cysts, and a classic “pear shaped” body appearance (obesity; although not always) and long term negative health consequences such as diabetes.

Metformin sensitizes the cells to insulin thus lowering the body’s production of insulin and consequently reducing androgen production. Once androgen production has been normalized ovulation can often resume. Metformin is dosed at 500 mg three times per day and Clomid or FSH may be added if ovulation is not established.

amber September 4, 2010 at 8:46 am

Yep.

I took it for 3 months and got pregnant.
I now have beautiful 6 month old baby girl.

Check out the website below for more info on your PCOS and message boards.

Good luck.

Jen September 4, 2010 at 8:46 am

I have been on glucophage for the past month, and am in the same boat as you (PCOS and slightly overweight.) In my case, I was put on it to try and regulate my insulin resistance associated with PCOS, and to balance me out, so that I begin to have a regular cycle, thus increasing my chances of conceiving.

Keysfergy September 4, 2010 at 8:46 am

hey I hear it does work, just have faith, I am currently on it and I have pcos this is my 1st month on it, it seems to be working because I had a real short period whicih I haven’t had a years, I am taking 500mg twice a day also, I did 3 cycle of clomid without any success, I am now taking clomid 100mg (3-7) with metformin, if it doesn’t work this month I’ll be taking injectables, I have a dr appointment on Friday, if metformin works for me I’ll keep u in touch, but every woman is different some will conceive some wouldn’t

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